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Further, due to burns, about 17% and 18% children have become temporarily and permanently differently abled, respectively, in 2018 in countries, such as Pakistan, Egypt, Colombia, and Bangladesh. This is indicative of the growing demand for wound care biologics to treat burn injuries. Biologics are biological agents, such as plant-derived active biomolecules, which help mend the innate repair mechanisms and have anti-microbial, anti-inflammatory, and anti-oxidant properties.

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Wound care biologics are used for the treatment of acute and chronic wounds. Acute wounds can be caused due to trauma or surgeries and progress through stages of wound healing. They usually heal completely within four weeks. These are either surgical, burn, or traumatic. By definition, even an incision made during a surgery can also be considered a wound. Chronic wounds develop and persist over time, and usually are a result of some other chronic condition.  One of the types of chronic wounds is the diabetic foot ulcer. These are commonly observed in diabetic patients, and in some cases, may even lead to amputation of the limb. Some common risk factors of diabetic foot ulcer are structural foot deformity, peripheral arterial occlusive disease, and diabetic neuropathy.

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